Snapshot of a phosphorylated substrate intermediate by kinetic crystallography

The ATP-dependent enzyme dethiobiotin synthetase from Escherichia coli catalyses the formation of dethiobiotin from CO(2) and 7,8-diaminopelargonic acid. The reaction is initiated by the formation of a carbamate and proceeds through a phosphorylated intermediate, a mixed carbamic phosphoric anhydrid...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Käck, Helena, Gibson, Katharine J., Lindqvist, Ylva, Schneider, Gunter
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20405/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9576910/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.10.5495
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