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Ohno's dilemma: Evolution of new genes under continuous selection

New genes with novel functions arise by duplication and divergence, but the process poses a problem. After duplication, an extra gene copy must rise to sufficiently high frequency in the population and remain free of common inactivating lesions long enough to acquire the rare mutations that provide...

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Detalhes bibliográficos
Main Authors: Bergthorsson, Ulfar, Andersson, Dan I., Roth, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040452/
https://ncbi.nlm.nih.gov/pubmed/17942681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707158104
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