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Drosophila follicle cell amplicons as models for metazoan DNA replication: A cyclinE mutant exhibits increased replication fork elongation

Gene clusters amplified in the ovarian follicle cells of Drosophila serve as powerful models for metazoan DNA replication. In response to developmental signals, specific genomic regions undergo amplification by repeated firing of replication origins and bidirectional movement of replication forks fo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Park, Eugenia A., MacAlpine, David M., Orr-Weaver, Terry L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040429/
https://ncbi.nlm.nih.gov/pubmed/17940024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707804104
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