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Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy

Cancer patients treated with antiangiogenic multitargeted receptor tyrosine kinase (RTK) inhibitors show increased levels of plasma VEGF and placental growth factor and decreased levels of soluble VEGF receptor-2, thus implicating these overall changes as a possible class effect of such drugs and ra...

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מידע ביבליוגרפי
Main Authors: Ebos, John M. L., Lee, Christina R., Christensen, James G., Mutsaers, Anthony J., Kerbel, Robert S.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040401/
https://ncbi.nlm.nih.gov/pubmed/17942672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708148104
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