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Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy

Cancer patients treated with antiangiogenic multitargeted receptor tyrosine kinase (RTK) inhibitors show increased levels of plasma VEGF and placental growth factor and decreased levels of soluble VEGF receptor-2, thus implicating these overall changes as a possible class effect of such drugs and ra...

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Detalhes bibliográficos
Main Authors: Ebos, John M. L., Lee, Christina R., Christensen, James G., Mutsaers, Anthony J., Kerbel, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040401/
https://ncbi.nlm.nih.gov/pubmed/17942672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708148104
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