An EF hand mutation in Stim1 causes premature platelet activation and bleeding in mice

Changes in cytoplasmic Ca(2+) levels regulate a variety of fundamental cellular functions in virtually all cells. In nonexcitable cells, a major pathway of Ca(2+) entry involves receptor-mediated depletion of intracellular Ca(2+) stores followed by the activation of store-operated calcium channels i...

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Hlavní autoři: Grosse, Johannes, Braun, Attila, Varga-Szabo, David, Beyersdorf, Niklas, Schneider, Boris, Zeitlmann, Lutz, Hanke, Petra, Schropp, Patricia, Mühlstedt, Silke, Zorn, Carolin, Huber, Michael, Schmittwolf, Carolin, Jagla, Wolfgang, Yu, Philipp, Kerkau, Thomas, Schulze, Harald, Nehls, Michael, Nieswandt, Bernhard
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2007
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040319/
https://ncbi.nlm.nih.gov/pubmed/17965774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32312
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