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Valsartan lowers brain β-amyloid protein levels and improves spatial learning in a mouse model of Alzheimer disease
Recent epidemiological evidence suggests that some antihypertensive medications may reduce the risk for Alzheimer disease (AD). We screened 55 clinically prescribed antihypertensive medications for AD-modifying activity using primary cortico-hippocampal neuron cultures generated from the Tg2576 AD m...
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Auteurs principaux: | , , , , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
American Society for Clinical Investigation
2007
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040315/ https://ncbi.nlm.nih.gov/pubmed/17965777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31547 |
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