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Forced Selection of tRNA(Glu) Reveals the Importance of Two Adenosine-Rich RNA Loops Within the U5-PBS for SIV(smmPBj) Replication

Simian immunodeficiency virus (SIV) and human immunodeficiency virus (HIV-1) preferentially select and use tRNA(Lys,3) as the primer for initiation of reverse transcription. Previous studies have shown that HIV-1 can be forced to use tRNA(Glu) if mutations are made within the primer-binding site (PB...

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Detalhes bibliográficos
Main Authors: Kelly, Maureen C., Kosloff, Barry R., Morrow, Casey D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040306/
https://ncbi.nlm.nih.gov/pubmed/17543363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.04.025
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