Importance of A-loop complementarity with tRNA(His )anticodon for continued selection of tRNA(His )as the HIV reverse transcription primer

BACKGROUND: Human immunodeficiency virus (HIV-1) preferentially selects tRNA(Lys,3 )as the primer for reverse transcription. HIV-1 can be forced to select alternative tRNAs through mutation in the primer-binding site (PBS) and a region upstream of the PBS designated as the A-loop. Alteration of the...

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Bibliographic Details
Main Authors: Ni, Na, Xu, Wenqin, Morrow, Casey D
Format: Artigo
Language:Inglês
Published: BioMed Central 2007
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785369/
https://ncbi.nlm.nih.gov/pubmed/17214904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-4-4
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