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Coevolution of a homing endonuclease and its host target sequence

We have determined the specificity profile of the homing endonuclease I-AniI and compared it to the conservation of its host gene. Homing endonucleases are encoded within intervening sequences such as group I introns. They initiate the transfer of such elements by cleaving cognate alleles lacking th...

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Hlavní autoři: Scalley-Kim, Michelle, McConnell-Smith, Audrey, Stoddard, Barry L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040299/
https://ncbi.nlm.nih.gov/pubmed/17720189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.07.052
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