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Inducible caspase 9 suicide gene to improve the safety of allodepleted T cells after haploidentical stem cell transplantation

Addback of donor T cells following T cell-depleted stem cell transplantation (SCT) can accelerate immune reconstitution and be effective against relapsed malignancy. After haploidentical SCT, a high risk of graft-versus-host disease (GVHD) essentially precludes this option, unless the T cells are fi...

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Hlavní autoři: Tey, Siok-Keen, Dotti, Gianpietro, Rooney, Cliona M., Heslop, Helen E., Brenner, Malcolm K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040267/
https://ncbi.nlm.nih.gov/pubmed/17640595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2007.04.005
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