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Synthesis of 7-Thiaarachidonic Acid as a Mechanistic Probe of Prostaglandin H Synthase-2
The mechanism by which prostaglandin synthase converts arachidonic acid to prostaglandin G(2), creating five new chiral centers in the process, is still incompletely understood. The first radical intermediate has been characterized by EPR spectroscopy but subsequent proposed intermediates have not s...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040112/ https://ncbi.nlm.nih.gov/pubmed/17485208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.04.073 |
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