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Selective quenching of fluorescence from unbound oligonucleotides by gold nanoparticles as a probe of RNA structure
Binding of small oligonucleotides to the periphery of folded RNA can provide insight into the secondary structure of complex RNA in solution. To discriminate between bound and unbound fluorescein-labeled 2′-O-methyl RNA probes, we use ionically coated gold nanoparticles to selectively adsorb unbound...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040090/ https://ncbi.nlm.nih.gov/pubmed/17895397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.138807 |
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