Binding and neutralization efficiencies of monoclonal antibodies, Fab fragments, and scFv specific for L1 epitopes on the capsid of infectious HPV particles

We compared the neutralization abilities of individual monoclonal antibodies (MAb) of two large panels reactive with L1 epitopes of HPV-11 or HPV-16. Binding titers were compared using both L1-only VLPs and to L1/L2 pseudovirions. While the VLPs were antigenically similar to the pseudovirions, clear...

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Bibliographic Details
Main Authors: Culp, Timothy D., Spatz, Christin M., Reed, Cynthia A., Christensen, Neil D.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040078/
https://ncbi.nlm.nih.gov/pubmed/17222883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.12.002
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