Basic fibroblast growth factor autocrine loop controls human osteosarcoma phenotyping and differentiation.

BACKGROUND: We focused on the phenotype of non-mineralizing MG 63 and mineralizing TE 85 human osteosarcoma cells and investigated the role of bFGF in modulating their differentiative responses. Basic FGF expression and bFGF effects on osteocalcin, runt-related transcription factor-2 (RUNX2), matrix...

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Main Authors: Bodo, Maria, Lilli, Cinzia, Bellucci, Catia, Carinci, Paolo, Calvitti, Mario, Pezzetti, Furio, Stabellini, Giordano, Bellocchio, Silvia, Balducci, Chiara, Carinci, Francesco, Baroni, Tiziano
Format: Artigo
Language:Inglês
Published: 2002
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040003/
https://ncbi.nlm.nih.gov/pubmed/12393937
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