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Unmasking the anti-La/SSB response in sera from patients with Sjogren's syndrome by specific blocking of anti-idiotypic antibodies to La/SSB antigenic determinants.

BACKGROUND: Autoantigen La/SSB is molecular target of humoral autoimmunity in patients with primary Sjogren's Syndrome (pSS) and systemic lupus erythematosus (SLE). In this study, we investigated the existence and possible influence of anti-idiotypic response to anti-La/SSB antibodies. MATERIAL...

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Detalhes bibliográficos
Main Authors: Routsias, John G., Touloupi, Evgenia, Dotsika, Eleni, Moulia, Avrilia, Tsikaris, Vassilios, Sakarellos, Constantinos, Sakarellos-Daitsiotis, Maria, Moutsopoulos, Haralampos M., Tzioufas, Athanasios G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039996/
https://ncbi.nlm.nih.gov/pubmed/12428060
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