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T cell help is required to induce idiotypic–anti-idiotypic autoantibody network after immunization with complementary epitope 289–308aa of La/SSB autoantigen in non-autoimmune mice

Immunotherapies against autoimmune diseases have been of limited success. Preventive vaccines could be developed on the basis to abrogate unwanted immune responses to defined autodeterminants. In this study it is shown that immunization of BALB/c mice with two linear T and B cell epitopes of the hum...

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Detalhes bibliográficos
Main Authors: PAPAMATTHEOU, M G, ROUTSIAS, J G, KARAGOUNI, E E, SAKARELLOS, C, SAKARELLOS-DAITSIOTIS, M, MOUTSOPOULOS, H M, TZIOUFAS, A G, DOTSIKA, E N
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808979/
https://ncbi.nlm.nih.gov/pubmed/15008973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02356.x
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