T cell help is required to induce idiotypic–anti-idiotypic autoantibody network after immunization with complementary epitope 289–308aa of La/SSB autoantigen in non-autoimmune mice

Immunotherapies against autoimmune diseases have been of limited success. Preventive vaccines could be developed on the basis to abrogate unwanted immune responses to defined autodeterminants. In this study it is shown that immunization of BALB/c mice with two linear T and B cell epitopes of the hum...

Full description

Saved in:
Bibliographic Details
Main Authors: PAPAMATTHEOU, M G, ROUTSIAS, J G, KARAGOUNI, E E, SAKARELLOS, C, SAKARELLOS-DAITSIOTIS, M, MOUTSOPOULOS, H M, TZIOUFAS, A G, DOTSIKA, E N
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2004
Subjects:
Animal Studies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808979/
https://ncbi.nlm.nih.gov/pubmed/15008973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02356.x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items