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Age-dependent decrease of synaptic plasticity in the neocortex of αCaMKII mutant mice

Synaptic long-term potentiation (LTP) and long-term depression (LTD) were studied in the visual cortex of mutant mice lacking α-calcium/calmodulin-dependent protein kinase II (αCaMKII). In adult mutants, little LTD or LTP could be elicited using standard conditioning protocols. However, substantial...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kirkwood, Alfredo, Silva, Alcino, Bear, Mark F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences of the USA 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC20378/
https://ncbi.nlm.nih.gov/pubmed/9096402
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