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One-Step Microbial Conversion of a Racemic Mixture of Pantoyl Lactone to Optically Active d-(—)-Pantoyl Lactone

Washed cells of Rhodococcus erythropolis IFO 12540 were found to convert only the l-(+)-isomer of pantoyl lactone to the d-(—)-isomer in a racemic mixture of pantoyl lactone. Under suitable reaction conditions, the amount of d-(—)-pantoyl lactone synthesized was 18.2 mg/ml (94.4% enantiomer excess;...

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Autori principali: Shimizu, Sakayu, Hattori, Shizuo, Hata, Hiroyuki, Yamada, Hideaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1987
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC203699/
https://ncbi.nlm.nih.gov/pubmed/16347301
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