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Stereoselective Reduction of Ethyl 4-Chloro-3-Oxobutanoate by a Microbial Aldehyde Reductase in an Organic Solvent-Water Diphasic System

Enzyme-catalyzed asymmetric reduction of ethyl 4-chloro-3-oxobutanoate in an organic solvent-water diphasic system was studied. NADPH-dependent aldehyde reductase isolated from Sporobolomyces salmonicolor AKU4429 and glucose dehydrogenase were used as catalysts for reduction of ethyl 4-chloro-3-oxob...

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Detalles Bibliográficos
Publicado en:Appl Environ Microbiol
Principais autores: Shimizu, Sakayu, Kataoka, Michihiko, Katoh, Masaaki, Morikawa, Tadashi, Miyoshi, Teruzo, Yamada, Hideaki
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1990
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184736/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16348250/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.56.8.2374-2377.1990
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