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Stereoselective Reduction of Ethyl 4-Chloro-3-Oxobutanoate by a Microbial Aldehyde Reductase in an Organic Solvent-Water Diphasic System

Enzyme-catalyzed asymmetric reduction of ethyl 4-chloro-3-oxobutanoate in an organic solvent-water diphasic system was studied. NADPH-dependent aldehyde reductase isolated from Sporobolomyces salmonicolor AKU4429 and glucose dehydrogenase were used as catalysts for reduction of ethyl 4-chloro-3-oxob...

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Detalhes bibliográficos
Main Authors: Shimizu, Sakayu, Kataoka, Michihiko, Katoh, Masaaki, Morikawa, Tadashi, Miyoshi, Teruzo, Yamada, Hideaki
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC184736/
https://ncbi.nlm.nih.gov/pubmed/16348250
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