Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands

A replication-deficient, recombinant adenovirus encoding human aquaporin-1 (hAQP1), the archetypal water channel, was constructed. This virus, AdhAQP1, directed hAQP1 expression in several epithelial cell lines in vitro. In polarized MDCK cell monolayers, hAQP1 was localized in the apical and basola...

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Bibliografische gegevens
Hoofdauteurs: Delporte, Christine, O’Connell, Brian C., He, Xinjun, Lancaster, Henry E., O’Connell, Anne C., Agre, Peter, Baum, Bruce J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences of the USA 1997
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC20358/
https://ncbi.nlm.nih.gov/pubmed/9096382
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