A Single Nucleotide Polymorphism in the DNA Polymerase Gamma Gene of Saccharomyces cerevisiae Laboratory Strains Is Responsible for Increased Mitochondrial DNA Mutability

In the Saccharomyces cerevisiae strains used for genome sequencing and functional analysis, the mitochondrial DNA replicase Mip1p contains a single nucleotide polymorphism changing the strictly conserved threonine 661 to alanine. This substitution is responsible for the increased rate of mitochondri...

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Hlavní autoři: Baruffini, Enrico, Lodi, Tiziana, Dallabona, Cristina, Foury, Françoise
Médium: Artigo
Jazyk:Inglês
Vydáno: Copyright © 2007 by the Genetics Society of America 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034627/
https://ncbi.nlm.nih.gov/pubmed/17720904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.079293
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