Effects of a polymorphism in the human tumor necrosis factor α promoter on transcriptional activation

Tumor necrosis factor α (TNFα) is a potent immunomodulator and proinflammatory cytokine that has been implicated in the pathogenesis of autoimmune and infectious diseases. For example, plasma levels of TNFα are positively correlated with severity and mortality in malaria and leishmaniasis. We have p...

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Bibliographic Details
Main Authors: Wilson, Anthony G., Symons, Julian A., McDowell, Tarra L., McDevitt, Hugh O., Duff, Gordon W.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences of the USA 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC20345/
https://ncbi.nlm.nih.gov/pubmed/9096369
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