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Human tryptophanyl-tRNA synthetase is switched to a tRNA-dependent mode for tryptophan activation by mutations at V85 and I311

For most aminoacyl-tRNA synthetases (aaRS), their cognate tRNA is not obligatory to catalyze amino acid activation, with the exception of four class I (aaRS): arginyl-tRNA synthetase, glutamyl-tRNA synthetase, glutaminyl-tRNA synthetase and class I lysyl-tRNA synthetase. Furthermore, for arginyl-, g...

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Detalhes bibliográficos
Main Authors: Guo, Li-Tao, Chen, Xiang-Long, Zhao, Bo-Tao, Shi, Yi, Li, Wei, Xue, Hong, Jin, You-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034488/
https://ncbi.nlm.nih.gov/pubmed/17726052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm633
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