The U1 snRNP-associated factor Luc7p affects 5′ splice site selection in yeast and human

yLuc7p is an essential subunit of the yeast U1 snRNP and contains two putative zinc fingers. Using RNA–protein cross-linking and directed site-specific proteolysis (DSSP), we have established that the N-terminal zinc finger of yLuc7p contacts the pre-mRNA in the 5′ exon in a region close to the cap....

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Bibliografiska uppgifter
Huvudupphovsmän: Puig, Oscar, Bragado-Nilsson, Elisabeth, Koski, Terhi, Séraphin, Bertrand
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2007
Ämnen:
RNA
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034479/
https://ncbi.nlm.nih.gov/pubmed/17726058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm505
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