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Molecular basis of Diamond–Blackfan anemia: structure and function analysis of RPS19

Diamond–Blackfan anemia (DBA) is a rare congenital disease linked to mutations in the ribosomal protein genes rps19, rps24 and rps17. It belongs to the emerging class of ribosomal disorders. To understand the impact of DBA mutations on RPS19 function, we have solved the crystal structure of RPS19 fr...

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Detalhes bibliográficos
Main Authors: Gregory, Lynn A., Aguissa-Touré, Almass-Houd, Pinaud, Noël, Legrand, Pierre, Gleizes, Pierre-Emmanuel, Fribourg, Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034476/
https://ncbi.nlm.nih.gov/pubmed/17726054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm626
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