Impaired ribosome biogenesis in Diamond-Blackfan anemia

The gene encoding the ribosomal protein S19 (RPS19) is frequently mutated in Diamond-Blackfan anemia (DBA), a congenital erythroblastopenia. The consequence of these mutations on the onset of the disease remains obscure. Here, we show that RPS19 plays an essential role in biogenesis of the 40S small...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Choesmel, Valérie, Bacqueville, Daniel, Rouquette, Jacques, Noaillac-Depeyre, Jacqueline, Fribourg, Sébastien, Crétien, Aurore, Leblanc, Thierry, Tchernia, Gil, Da Costa, Lydie, Gleizes, Pierre-Emmanuel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2007
Pynciau:
Red Cells
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785132/
https://ncbi.nlm.nih.gov/pubmed/17053056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-038372
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