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Suppression of gross chromosomal rearrangements by a new alternative replication factor C complex
Defects in DNA replication fidelity lead to genomic instability. Gross chromosomal rearrangement (GCR), a type of genomic instability, is highly enhanced by various initial mutations affecting DNA replication. Frequent observations of GCRs in many cancers strongly argue the importance to maintain hi...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2034446/ https://ncbi.nlm.nih.gov/pubmed/17689491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.07.126 |
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