Early electrical remodeling in rabbit pulmonary vein results from trafficking of intracellular SK2 channels to membrane sites

OBJECTIVE: Atrial fibrillation is often initiated by bursts of ectopic activity arising in the pulmonary veins. We have previously shown that a 3-h intermittent burst pacing protocol (BPP), mimicking ectopic pulmonary vein foci, shortens action potential duration (APD) locally at the pulmonary vein-...

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Main Authors: Ozgen, Nazira, Dun, Wen, Sosunov, Eugene A., Anyukhovsky, Evgeny P., Hirose, Masanori, Duffy, Heather S., Boyden, Penelope A., Rosen, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034441/
https://ncbi.nlm.nih.gov/pubmed/17588552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardiores.2007.05.008
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