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DOPAMINE RECEPTOR ACTIVATION REVEALS A NOVEL, KYNURENATE-SENSITIVE COMPONENT OF STRIATAL NMDA NEUROTOXICITY

The N-methyl-D-aspartate (NMDA) subtype of glutamate receptors plays an important role in brain physiology, but excessive receptor stimulation results in seizures and excitotoxic nerve cell death. NMDA receptor-mediated neuronal excitation and injury can be prevented by high, non-physiological conce...

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Détails bibliographiques
Auteurs principaux: Poeggeler, Burkhard, Rassoulpour, Arash, Wu, Hui-Qiu, Guidetti, Paolo, Roberts, Rosalinda C., Schwarcz, Robert
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034343/
https://ncbi.nlm.nih.gov/pubmed/17629627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.05.033
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