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Concentration-Dependent Interactions of the Organophosphates Chlorpyrifos Oxon and Methyl Paraoxon with Human Recombinant Acetylcholinesterase

For many decades it has been thought that oxygen analogs (oxons) of organophosphorus insecticides phosphylate the catalytic site of acetylcholinesterase by a mechanism that follows simple Michaelis-Menten kinetics. More recently, the interactions of at least some oxons have been shown to be far more...

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Detalhes bibliográficos
Main Authors: Kaushik, R., Rosenfeld, Clint A., Sultatos, L.G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034337/
https://ncbi.nlm.nih.gov/pubmed/17467020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2007.03.013
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