Lack of NF-κB1 (p105/p50) Attenuates Unloading-induced Downregulation of PPARα and PPARα-regulated Gene Expression in Rodent Heart

OBJECTIVE: Unloading of the rodent heart activates the fetal gene program, decreases peroxisome proliferator-activated receptor α (PPARα) and PPARα-regulated gene expression (MCAD), and induces cardiomyocyte atrophy. NF-κB regulates the fetal gene program and PPARα-regulated gene expression during c...

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Main Authors: Razeghi, Peter, Wang, Mou-Er, Youker, Keith A., Golfman, Leonard, Stepkowski, Stanislaw, Taegtmeyer, Heinrich
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034318/
https://ncbi.nlm.nih.gov/pubmed/17276423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardiores.2006.12.021
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