Sgs1, a Bloom’s helicase ortholog, prevents aberrant crossing-over by suppressing the formation of multi-chromatid joint molecules

Bloom’s helicase (BLM) is thought to prevent crossing-over during DNA double-strand-break repair (DSBR) by disassembling double Holliday Junctions (dHJs) or by preventing their formation. We show that Saccharomyces cerevisiae BLM ortholog, Sgs1, prevents aberrant crossing-over during meiosis by supp...

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Detalhes bibliográficos
Main Authors: Oh, Steve D., Lao, Jessica P., Hwang, Patty Yi-Hwa, Taylor, Andrew F., Smith, Gerald R., Hunter, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034285/
https://ncbi.nlm.nih.gov/pubmed/17662941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.05.035
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