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Polyomavirus JC Infects Human Brain Microvascular Endothelial Cells Independent of Serotonin Receptor 2A

Although human polyomavirus JC (JCV) is known to cause progressive multifocal leukoencephalopathy (PML) in immunocompromised individuals, the mechanism by which, JCV crosses the blood-brain barrier (BBB) remains unclear. To test our hypothesis that cell-free JCV gains entry into the brain by infecti...

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Detalhes bibliográficos
Main Authors: Chapagain, Moti L., Verma, Saguna, Mercier, Frederic, Yanagihara, Richard, Nerurkar, Vivek R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034208/
https://ncbi.nlm.nih.gov/pubmed/17399760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.02.018
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