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Serotonin Receptor 2A blocker (Risperidone) has no effect on Human Polyomavirus JC Infection of Primary Human Fetal Glial cells

A recent report demonstrated that JCV employs serotonin receptor 2A (5HT(2A)R) to infect the glial cells. To assess the ability of a potent 5HT(2A)R blocker, risperidone, to inhibit JCV infection, we treated primary human fetal glial (PHFG) cells in-vitro with risperidone for 24 hr and inoculated wi...

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Detalhes bibliográficos
Main Authors: Chapagain, Moti L., Sumibcay, Laarni, Gurjav, Ulziijargal, Kaufusi, Pakieli H., Kast, Richard E., Nerurkar, Vivek R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684460/
https://ncbi.nlm.nih.gov/pubmed/18989819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13550280802235916
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