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Decreased tyrosine phosphorylation in tumour cells resistant to FCE 24517 (tallimustine).

Resistance to FCE 24517 is not related to the emergence of any of the most frequently observed phenotypes. We have found that two resistant cell lines (L1210/24517 murine leukaemia and LoVo/24517 human colon adenocarcinoma) present congenital modifications in tyrosyl phosphatase and kinase activitie...

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Autori principali: Ciomei, M., Pastori, W., Capolongo, L., Geroni, C., Melegaro, G., Pennella, G., Grandi, M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034097/
https://ncbi.nlm.nih.gov/pubmed/8519667
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