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DT-diaphorase activity in normal and neoplastic human tissues; an indicator for sensitivity to bioreductive agents?

DT-diaphorase (DTD) is an important enzyme for the bioreductive activation of the new alkylating indoloquinone EO9. In preclinical studies, EO9 has shown selective anti-tumour activity against solid tumours and under hypoxic conditions. The levels of three reductive enzymes have been determined in t...

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Detaylı Bibliyografya
Asıl Yazarlar: Smitskamp-Wilms, E., Giaccone, G., Pinedo, H. M., van der Laan, B. F., Peters, G. J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 1995
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034035/
https://ncbi.nlm.nih.gov/pubmed/7547240
Etiketler: Etiketle
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