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Intracellular metabolites of mercaptopurine in children with lymphoblastic leukaemia: a possible indicator of non-compliance?

As part of a programme assessing the pharmacokinetics of oral thiopurines given for lymphoblastic leukaemia, we assayed intracellular metabolites of mercaptopurine in children from all over the United Kingdom who were given a standard dose of the drug. The metabolites we measured, thioguanine nucleo...

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Autors principals: Lennard, L., Welch, J., Lilleyman, J. S.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034028/
https://ncbi.nlm.nih.gov/pubmed/7547211
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