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8-Chloro-cAMP induces apoptotic cell death in a human mammary carcinoma cell (MCF-7) line.

8-Cl-cAMP and 8-NH2-cAMP induced MCF-7 cell death. The type(s) of cell death were studied in more detail and compared with the cell death type (apoptosis) induced by okadaic acid, an inhibitor of serine/threonine phosphatases. By morphological criteria dying cells showed loss of cell-cell interactio...

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Autors principals: Bøe, R., Gjertsen, B. T., Døskeland, S. O., Vintermyr, O. K.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033955/
https://ncbi.nlm.nih.gov/pubmed/7577461
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