Phase II and pharmacokinetic study of lobaplatin in patients with relapsed ovarian cancer.

In phase I studies, lobaplatin showed activity in ovarian cancer patients pretreated with platinum. A phase II trial with lobaplatin was performed in patients with refractory or relapsed ovarian cancer to define activity and pharmacokinetics. Twenty-two patients were treated with lobaplatin administ...

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Main Authors: Gietema, J. A., Veldhuis, G. J., Guchelaar, H. J., Willemse, P. H., Uges, D. R., Cats, A., Boonstra, H., van der Graaf, W. T., Sleijfer, D. T., de Vries, E. G.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033845/
https://ncbi.nlm.nih.gov/pubmed/7779728
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