Coexpression of cdk2/cdc2 and retinoblastoma gene products in colorectal cancer.

The retinoblastoma gene (Rb gene) is a tumour-suppressor gene and its product (pRB) is known to act as a negative regulator of the cell cycle. Although lack of pRB expression resulting from gene alterations is considered to be responsible for the genesis of several human malignancies, increased expr...

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Main Authors: Yamamoto, H., Monden, T., Ikeda, K., Izawa, H., Fukuda, K., Fukunaga, M., Tomita, N., Shimano, T., Shiozaki, H., Monden, M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033831/
https://ncbi.nlm.nih.gov/pubmed/7779716
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