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Folding of the conserved domain but not of flanking regions in the integrin β(2) subunit requires association with the α subunit

We have used immunoprecipitation with mAbs to probe folding during biosynthesis of the β(2) integrin subunit of lymphocyte function-associated antigen 1 (LFA-1; CD11a/CD18) before and after association with the α(L) subunit. An evolutionarily conserved region is present in the β(2) subunit between a...

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Sonraí Bibleagrafaíochta
Main Authors: Huang, Chichi, Lu, Chafen, Springer, Timothy A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences of the USA 1997
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC20338/
https://ncbi.nlm.nih.gov/pubmed/9096362
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