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Increased protein kinase or decreased PP2A activity bypasses sphingoid base requirement in endocytosis

Lipids have been implicated in signal transduction and in several stages of membrane trafficking, but these two functions have not been functionally linked. In yeast, sphingoid base synthesis is required for the internalization step of endocytosis and organization of the actin cytoskeleton. We show...

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Detalles Bibliográficos
Main Authors: Friant, Sylvie, Zanolari, Bettina, Riezman, Howard
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC203374/
https://ncbi.nlm.nih.gov/pubmed/10856229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.12.2834
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