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Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast
In yeast, sphingoid base synthesis is required for the internalization step of endocytosis and organization of the actin cytoskeleton. We show that overexpression of either one of the two kinases Pkh1p or Pkh2p, that are homologous to mammalian 3-phosphoinositide-dependent kinase-1 (PDK1), can speci...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125749/ https://ncbi.nlm.nih.gov/pubmed/11726514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.23.6783 |
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