Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast

In yeast, sphingoid base synthesis is required for the internalization step of endocytosis and organization of the actin cytoskeleton. We show that overexpression of either one of the two kinases Pkh1p or Pkh2p, that are homologous to mammalian 3-phosphoinositide-dependent kinase-1 (PDK1), can speci...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Friant, Sylvie, Lombardi, Ruben, Schmelzle, Tobias, Hall, Michael N., Riezman, Howard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11726514/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.23.6783
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