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Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast

In yeast, sphingoid base synthesis is required for the internalization step of endocytosis and organization of the actin cytoskeleton. We show that overexpression of either one of the two kinases Pkh1p or Pkh2p, that are homologous to mammalian 3-phosphoinositide-dependent kinase-1 (PDK1), can speci...

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Bibliographische Detailangaben
Hauptverfasser: Friant, Sylvie, Lombardi, Ruben, Schmelzle, Tobias, Hall, Michael N., Riezman, Howard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC125749/
https://ncbi.nlm.nih.gov/pubmed/11726514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.23.6783
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