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Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast

In yeast, sphingoid base synthesis is required for the internalization step of endocytosis and organization of the actin cytoskeleton. We show that overexpression of either one of the two kinases Pkh1p or Pkh2p, that are homologous to mammalian 3-phosphoinositide-dependent kinase-1 (PDK1), can speci...

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Main Authors: Friant, Sylvie, Lombardi, Ruben, Schmelzle, Tobias, Hall, Michael N., Riezman, Howard
格式: Artigo
語言:Inglês
出版: Oxford University Press 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC125749/
https://ncbi.nlm.nih.gov/pubmed/11726514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.23.6783
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