Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast

In yeast, sphingoid base synthesis is required for the internalization step of endocytosis and organization of the actin cytoskeleton. We show that overexpression of either one of the two kinases Pkh1p or Pkh2p, that are homologous to mammalian 3-phosphoinositide-dependent kinase-1 (PDK1), can speci...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Friant, Sylvie, Lombardi, Ruben, Schmelzle, Tobias, Hall, Michael N., Riezman, Howard
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2001
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11726514/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.23.6783
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