Indoloquinone EO9: DNA interstrand cross-linking upon reduction by DT-diaphorase or xanthine oxidase.

We report DNA interstrand cross-linking caused by the anti-tumour indoloquinone EO9 following reductive activation with purified rat liver DT-diaphorase or xanthine oxidase. Reduction was a necessary event for cross-linking to occur. DNA cross-link formation by EO9 following DT-diaphorase reduction...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Maliepaard, M., Wolfs, A., Groot, S. E., de Mol, N. J., Janssen, L. H.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1995
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033736/
https://ncbi.nlm.nih.gov/pubmed/7536024
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki