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Inhibition of gastric cancer cell proliferation by antisense oligonucleotides targeting the messenger RNA encoding proliferating cell nuclear antigen.

Proliferating cell nuclear antigen (PCNA) is a nuclear protein that regulates DNA synthesis by DNA polymerase delta, and is essential for DNA replication. PCNA expression level is related to the malignancy of gastric cancer cells. Seven different gastric cancer cell lines and two kinds of control ce...

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Autors principals: Sakakura, C., Hagiwara, A., Tsujimoto, H., Ozaki, K., Sakakibara, T., Oyama, T., Ogaki, M., Takahashi, T.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033708/
https://ncbi.nlm.nih.gov/pubmed/7981055
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