Lack of a correlation between micronucleus formation and radiosensitivity in established and primary cultures of human tumours.

The radiation-induced genotoxic damage in three established cell lines and 15 primary cultures of human malignant melanoma and ovarian carcinoma showing different radiosensitivity was tested by the cytokinesis-block micronucleus assay. A dose-related increase in micronucleus frequency was observed i...

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Bibliographic Details
Main Authors: Villa, R., Zaffaroni, N., Gornati, D., Costa, A., Silvestrini, R.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033705/
https://ncbi.nlm.nih.gov/pubmed/7981062
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