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Structure of tandem RNA recognition motifs from polypyrimidine tract binding protein reveals novel features of the RRM fold

Polypyrimidine tract binding protein (PTB), an RNA binding protein containing four RNA recognition motifs (RRMs), is involved in both pre-mRNA splicing and translation initiation directed by picornaviral internal ribosome entry sites. Sequence comparisons previously indicated that PTB is a non-canon...

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Bibliographic Details
Published in:EMBO J
Main Authors: Conte, Maria R., Grüne, Tim, Ghuman, Jamie, Kelly, Geoff, Ladas, Anastasia, Matthews, Stephen, Curry, Stephen
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2000
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203357/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10856256/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.12.3132
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