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Molecular genetic analysis of flow-sorted ovarian tumour cells: improved detection of loss of heterozygosity.

Detection of loss of heterozygosity (LOH) is usually performed on homogenised tumour specimens. In this type of analysis samples with a low percentage of tumour cells have to be excluded and possible intra-tumour heterogeneity is obscured. In this study we report the application of polymerase chain...

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Detalhes bibliográficos
Main Authors: Abeln, E. C., Corver, W. E., Kuipers-Dijkshoorn, N. J., Fleuren, G. J., Cornelisse, C. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033519/
https://ncbi.nlm.nih.gov/pubmed/8054273
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